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Study identifier: NCT06859164 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Genicular Artery Embolization for Reducing Pain in Medically Refractory Symptomatic Knee Osteoarthritis

Condition: Knee Osteoarthritis · Knee Osteoarthritis (Knee OA) · Knee Osteoarthritis (OA)  ·  Sponsor: University of Chicago

PhasePhase 2
Planned participants50
Who can joinAll sexes, 40 Years to 80 Years
Healthy volunteersNo

About this study

Genicular Artery Embolization for Reducing Pain in Symptomatic Knee Osteoarthritis: A Pilot Randomized Sham-Controlled Study (SHAM-PAIN) is a NIH-NIAMS funded project designed to assess enrollment feasibility and detect any differences between GAE and a similar sham intervention in reducing KOA-related pain at 3 months as measured by the Knee injury and Osteoarthritis Outcome Score (KOOS) pain subscore. Additionally, this study aims to determine the magnitude of difference in pain response between GAE and sham to adequately power a larger, more definitive randomized sham-controlled trial (RCT). The influence of psychosocial and psychocognitive factors, changes in analgesic use, and conditions of knee joint cartilage and effusion will similarly be explored to determine their impacts on perceived pain response to GAE.

This description comes directly from the study's public registry record.

Talk to the study team

Osman Ahmed, MD  ·  8478124513  ·  OAhmed@bsd.uchicago.edu

Faisal F Al-Qawasmi  ·  t-9falqa@uchicago.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of ChicagoChicago, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06859164