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Study identifier: NCT06857942 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

Condition: Psoriasis · Overweight or Obesity  ·  Sponsor: Eli Lilly and Company

PhasePhase 4
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The main purpose of this study is to assess the effectiveness of adding tirzepatide to ixekizumab therapy in standard clinical practice in participants with moderate-to-severe plaque PsO and obesity or overweight with at least 1 weight-related comorbidity. The study will last up to 12 months.

This description comes directly from the study's public registry record.

Talk to the study team

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or  ·  1-317-615-4559  ·  LillyTrials@Lilly.com

Physicians interested in becoming principal investigators please contact  ·  clinical_inquiry_hub@lilly.com

Always discuss trial participation with your own doctor first.

Locations (40)

Medical Dermatology SpecialistsPhoenix, Arizona, United StatesRecruiting
First OC Dermatology Research IncFountain Valley, California, United StatesRecruiting
Center For Dermatology Clinical Research, Inc.Fremont, California, United StatesRecruiting
Metropolis DermatologyLos Angeles, California, United StatesRecruiting
Northridge Clinical TrialsNorthridge, California, United StatesRecruiting
NeoClinical ResearchHialeah, Florida, United StatesRecruiting
Skin Care ResearchHollywood, Florida, United StatesRecruiting
Encore Medical ResearchHollywood, Florida, United StatesRecruiting
MOORE Clinical Research, Inc. d/b/a TrueBlue Clinical ResearchTampa, Florida, United StatesRecruiting
TruDerm & TruSpaWellington, Florida, United StatesRecruiting
Southeast Research SpecialistsDouglasville, Georgia, United StatesRecruiting
Dawes Fretzin Clinical Research Group, LLCIndianapolis, Indiana, United StatesRecruiting

+ 28 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06857942