Condition: Burns · Contracture Scar · Surgical Injury · Sponsor: University of Pittsburgh
The goal of this study is to explore if an adipose-based therapeutic strategy can treat contracted scars secondary to soft-tissue burn wounds in injured individuals, especially those with severe burns or soft-tissue loss. The main question it aims to answer are: \- Can autologous layered composite grafting demonstrate non-inferiority compared to full-thickness skin grafting for delayed reconstruction of post-burn or trauma scar contracture? Researchers will compare the single-stage autologous layered composite grafting method to traditional methods to see if it improves healing outcomes, minimizes scarring, and reduces infection risk. Participants will: * Receive fat grafting at time of scar revision. * Undergo simultaneous split-thickness skin grafting for full soft-tissue reconstruction.
This description comes directly from the study's public registry record.
Eleanor Shirley · 412-641-8676 · shirleye@upmc.edu
Patsy Simon · 412-641-8676 · simopa@UPMC.EDU
Always discuss trial participation with your own doctor first.
| Mercy Hospital | Pittsburgh, Pennsylvania, United States | Recruiting |
| Presbyterian Hospital | Pittsburgh, Pennsylvania, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06857435