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Study identifier: NCT06855329 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis

Condition: Progressive Pulmonary Fibrosis · Interstitial Lung Disease  ·  Sponsor: University of Massachusetts, Worcester

PhaseN/A
Planned participants500
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This is a prospective, observational cohort study. Participants with non-idiopatic pulmonary fibrosis, interstitial lung disease (ILD) will be followed for 24 months to systematically collect clinical, imaging, and biospecimen data. The primary objective is to optimize progressive pulmonary fibrosis (PPF) classification and establish PPF incidence for key ILD subtypes. Additional exploratory objectives are to 1) Prospectively validate a novel PPF classifier and assess performance durability over time, and 2) Determine whether multi-dimensional PPF prediction outperforms component approaches.

This description comes directly from the study's public registry record.

Talk to the study team

Fernando J Martinez, MD, MS  ·  508-334-8685  ·  fernando.martinez1@umassmed.edu

Elizabeth Peters, BSN  ·  774-455-4432  ·  elizabeth.peters2@umassmed.edu

Always discuss trial participation with your own doctor first.

Locations (13)

University of Massachusetts Chan Medical SchoolWorcester, Massachusetts, United StatesRecruiting
University of MichiganAnn Arbor, Michigan, United StatesRecruiting
University of Texas SouthwesternDallas, Texas, United StatesNot Yet Recruiting
University of VirginiaCharlottesville, Virginia, United StatesNot Yet Recruiting
University of WashingtonSeattle, Washington, United StatesNot Yet Recruiting
Royal Prince Alfred HospitalCamperdown, New South Wales, AustraliaNot Yet Recruiting
Prince Charles HospitalBrisbane, Queensland, AustraliaNot Yet Recruiting
Austin HealthMelbourne, Victoria, AustraliaNot Yet Recruiting
University of CalgaryCalgary, Alberta, CanadaNot Yet Recruiting
University of British ColumbiaVancouver, British Columbia, CanadaNot Yet Recruiting
University College DublinDublin, Ireland, IrelandNot Yet Recruiting
Royal BromptonLondon, Greater London, United KingdomNot Yet Recruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06855329