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Study identifier: NCT06854757 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Families Left Behind

Condition: Grief · Grief Disorder, Prolonged · Overdose Accidental  ·  Sponsor: RAND

PhaseNA
Planned participants340
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The United States is facing unprecedented rates of drug overdose deaths, profoundly impacting millions of families who are left to navigate their grief. Those bereaved by overdose experience a unique form of grief characterized by feelings of guilt, shame, and blame, which can worsen their suffering and deter them from seeking help. Individuals coping with overdose loss often endure more severe health consequences compared to those grieving non-drug related deaths, including prolonged grief disorder, substance use disorders, PTSD, depression, and suicidal thoughts. Moreover, bereaved individuals, particularly those with a history of substance use, may engage in risky behaviors as a means of coping, further exacerbating the risk of overdose and mortality within this vulnerable population. Peer grief support interventions have emerged as a promising approach to assist those experiencing such losses. To combat these outcomes, we are collaborating with Peer Community Support Partners (PSCP) in a novel practice-research partnership to implement the RIVER peer grief support model. Though RIVER has shown success in community settings, it has yet to be rigorously evaluated. In a three-aim approach, this study aims to assess the effectiveness of the RIVER model while also enhancing and engaging grievers with support resources via medical examiner offices (MEOs), which routinely contact families during death investigations. This research represents a pivotal advancement in addressing t…

This description comes directly from the study's public registry record.

Talk to the study team

Alison Athey, PhD  ·  (703) 413-1100  ·  aathey@rand.org

Karen Osilla, PhD  ·  kosilla@stanford.edu

Always discuss trial participation with your own doctor first.

Locations (4)

Jefferson County Coroner/Medical Examiner's OfficeBirmingham, Alabama, United StatesRecruiting
San Diego County Medical Examiner OfficeSan Diego, California, United StatesRecruiting
Connecticut Office of the Chief Medical ExaminerFarmington, Connecticut, United StatesRecruiting
Peer Support Community PartnersWatertown, Massachusetts, United StatesActive Not Recruiting

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Source record: clinicaltrials.gov/study/NCT06854757