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Study identifier: NCT06854653 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase 2 Study of PTX 100 in Patients With Relapsed/Refractory CTCL

Condition: CTCL  ·  Sponsor: Prescient Therapeutics, Ltd.

PhasePhase 2
Planned participants115
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is an open-label, phase 2 randomized study to evaluate the efficacy, safety, pharmacokinetics (PK) and pharmadynamics (PD), of PTX-100 monotherapy at 500 or 1000 mg/m2 in patients with relapsed/refractory Cutaneous T-Cell Lymphoma (CTCL). PTX-100 will be administered by IV infusion over 60 minutes on days 1 to 5 of a 14-day cycle for 4 cycles, then 21 day cycle thereafter. Subjects will be treated or followed up, if subjects discontinue treatment, for up to 18 months.

This description comes directly from the study's public registry record.

Talk to the study team

Upaly Bahadure  ·  +61 3 9692 7222  ·  upaly@ptxtherapeutics.com

David Wong  ·  david.wong@ptxtherapeutics.com

Always discuss trial participation with your own doctor first.

Locations (15)

City of Hope Comprehensive Cancer CenteDuarte, California, United StatesRecruiting
University of California IrvineIrvine, California, United StatesRecruiting
Yale Cancer CenterNew Haven, Connecticut, United StatesRecruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Rochester Skin Lymphoma Medical Group. PLLCRochester, New York, United StatesRecruiting
Virginia Commonwealth University Massey Comprehensive Cancer CenteRichmond, Virginia, United StatesRecruiting
Westmead HospitalWestmead, New South Wales, AustraliaRecruiting
Epworth HealthcareMelbourne, Victoria, AustraliaRecruiting
Linear Clinical ResearchNedlands, Western Australia, AustraliaRecruiting
CHU de Bordeaux - Hopital Saint AndréBordeaux, Bordeaux, FranceNot Yet Recruiting
Hopital Lyon SudLyon, Pierre-Benite, FranceNot Yet Recruiting
Hopital Saint LouisParis, Île-de-France Region, FranceNot Yet Recruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06854653