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Study identifier: NCT06853938 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Optimizing Transhumeral Osseointegration Prosthesis Control

Condition: Transhumeral Amputation  ·  Sponsor: University of Alberta

PhaseNA
Planned participants5
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

Upper limb amputation above the elbow results in a significant loss of function. There have been many advancements in surgery and prosthetic devices to restore arm function, but many people still reject upper limb prostheses. This is due to difficulties with how the socket fits and poor control of the device. Above-elbow prostheses are particularly challenging to use for several reasons. The socket must go all the way into the shoulder for stability. To hold the prosthesis onto the remaining arm, there needs to be a strap across the chest and shoulder. The prosthesis can be heavy, and the socket can slip or move around. This makes it hard to use muscle signals in the residual limb to control advanced prosthetic devices. People with limb loss are interested in advanced prostheses to use them reliably for day-to-day activities. Bone-anchored prostheses (BAPs) are a new approach. They are for people with upper limb loss who can't use socket prostheses. The surgery involves putting a titanium rod into the remaining bone, which, over time, joins with the bone. This implant extends through the skin. It enables the direct attachment of the prosthetic parts (like the elbow and hand). With BAPs, there is no need for a socket. Also, there is a well-known surgery called "Targeted muscle reinnervation" (TMR). It improves the number of arm muscle control signals. These signals are used to control myoelectric prostheses. However, after both these surgeries, there is a lack of research tha…

This description comes directly from the study's public registry record.

Talk to the study team

Jacqueline S Hebert, MD, FRCPC  ·  780-492-7846  ·  jhebert@ualberta.ca

Mayank Rehani, MSc  ·  780-492-4736  ·  rehani@ualberta.ca

Always discuss trial participation with your own doctor first.

Locations (2)

Glenrose Rehabilitation HospitalEdmonton, Alberta, CanadaRecruiting
University of AlbertaEdmonton, Alberta, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06853938