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Study identifier: NCT06853912 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)

Condition: Alcohol Use Disorder (AUD) · PTSD  ·  Sponsor: Nathan Brashares Sackett

PhasePhase 2
Planned participants40
Who can joinAll sexes, 21 Years to 65 Years
Healthy volunteersNo

About this study

This study is a phase 2 single-site, double-blind, placebo-controlled, randomized clinical trial with an open-label extension phase to examine the safety of psilocybin (25 mg) combined with psychological support (Psi-PS) for treatment of approximately 40 military veterans and first responders (ages 21-65) with co-occurring alcohol use disorder (AUD) and posttraumatic stress disorder (PTSD). Psychological support is defined as providing safety, reassurance, active listening, and empathetic presence during the drug administration session in a nondirective manner. We hypothesize that Psi-PS may provide a safe treatment for participants. The primary objective of study is to characterize the safety of psilocybin combined with psychological support (Psi-PS) for individuals with co-occurring alcohol use disorder (AUD) and PTSD.

This description comes directly from the study's public registry record.

Talk to the study team

Christina Sargent  ·  206-543-5941  ·  sargec2@uw.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Washington Center for Novel Therapeutics in Addiction PsychiatrySeattle, Washington, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06853912