Condition: Preoperative Anxiety · Preoperative Sedation · Children · Sponsor: Second Affiliated Hospital of Wenzhou Medical University
For pediatric patients undergoing general anesthesia, poor anesthesia induction compliance often has adverse effects on individual behavior in the early postoperative period. Dexmedetomidine can reduce the cardiovascular responses and postoperative mental adverse reactions caused by esketamine anesthesia induction \[6\]. This study aims to explore the ED50 and ED95 and clinical effects of the combination of dexmedetomidine and esketamine nasal drops for preoperative sedation in children of different ages undergoing general anesthesia, providing a theoretical basis for the combined use of dexmedetomidine and esketamine for preoperative sedation in children undergoing general anesthesia.
This description comes directly from the study's public registry record.
Huacheng Liu · 18957755138 · huachengliu@163.com
Chenrui Zhou · 15157910160 · zcr934419@163.com
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| The second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University | Wenzhou, Zhejiang, China | Not Yet Recruiting |
| The second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University | Wenzhou, Zhejiang, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06853431