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Study identifier: NCT06852222 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

Condition: Leukemia, Myeloid, Acute  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 3
Planned participants600
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to assess how bleximenib and Venetoclax (VEN)+ Azacitidine (AZA) works as compared to placebo and VEN+AZA alone for the treatment of participants with newly diagnosed Acute Myeloid Leukemia (AML) with a mutation in the NPM1 or KMT2A gene.

This description comes directly from the study's public registry record.

Talk to the study team

Study Contact  ·  844-434-4210  ·  Participate-In-This-Study1@its.jnj.com

Always discuss trial participation with your own doctor first.

Locations (253)

University of Alabama at BirminghamBirmingham, Alabama, United StatesRecruiting
Cancer Treatment Center of America PhoenixGoodyear, Arizona, United StatesRecruiting
The University of Arizona Cancer CenterTucson, Arizona, United StatesRecruiting
University of Arkansas at Little RockLittle Rock, Arkansas, United StatesRecruiting
City of HopeDuarte, California, United StatesRecruiting
Rocky Mountain Cancer CentersAurora, Colorado, United StatesRecruiting
Medical Oncology Hematology Consultants, PANewark, Delaware, United StatesRecruiting
Florida Cancer Specialists & Research InstituteFort Myers, Florida, United StatesRecruiting
Jupiter ResearchJupiter, Florida, United StatesRecruiting
Orlando Health Cancer InstituteOrlando, Florida, United StatesRecruiting
Memorial Cancer InstitutePembroke Pines, Florida, United StatesRecruiting
Moffit Cancer centerTampa, Florida, United StatesRecruiting

+ 241 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06852222