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Study identifier: NCT06849752 Synced from ClinicalTrials.gov · July 29, 2026
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Early Assessment and Initiation of GuideLine-Directed Evidence-Based Management-HF

Condition: Heart Failure · Socioeconomic Adversity  ·  Sponsor: The Cleveland Clinic

PhaseN/A
Planned participants1000
Who can joinAll sexes, 40 Years to no upper limit
Healthy volunteersNo

About this study

EAGLE-HF (Early Assessment and initiation of GuideLine-directed Evidence-based management-HF) is a prospective single site study of a multinational, unblinded, randomized-controlled, longitudinal trial called SYMPHONY. Primary, secondary and exploratory outcomes that are part of SYMPHONY are not described herein as they replicate SYMPHONY outcomes. Data associated with SYMPHONY outcomes will be sent to the SYMPHONY coordinating center. In EAGLE-HF, site investigators will examine if a new-onset heart failure (HF) diagnosis are asscoiated with social determinants of health (6 factors), social vulnerability index and distressed community indices. In addition, for patients diagnosed with HFrEF, prescribing patterns (use of and dose of) core HF medications will be assessed for association with physician practice type and medical provider type. Finally, (among participants in the SYMPHONY Active arm, an optimal NTproBNP cut-point will be assessed for diagnosis of HF based on social determinants of health, social vulnerability index, distressed community index, HF risk factors and medical comorbidities.

This description comes directly from the study's public registry record.

Talk to the study team

Nancy M Albert, PhD  ·  2163129191  ·  albertn@ccf.org

Michelle Levay, MSN  ·  1-216-445-4749  ·  levaym@ccf.org

Always discuss trial participation with your own doctor first.

Locations (1)

Cleveland ClinicCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06849752