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Study identifier: NCT06848751 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Tubeless Surgery With Impaired Pulmonary Function

Condition: Lung Function Decreased · Surgery  ·  Sponsor: The Second Hospital of Shandong University

PhaseNA
Planned participants45
Who can joinAll sexes, 14 Years to 85 Years
Healthy volunteersNo

About this study

Some patients with impaired lung function require minimally invasive surgical treatment, including those with lung cancer, benign lung tumors, pneumothorax, or lung volume reduction surgery. Patients with borderline lung function often cannot be extubated immediately postoperatively under conventional treatment models. These patients typically need to be transferred to the surgical ICU for close monitoring. However, positive-pressure mechanical ventilation with an endotracheal tube carries risks of further airway injury and persistent air leakage from the lung surface, leading to a high incidence of postoperative respiratory failure. Non-intubated minimally invasive surgery (tubeless), which preserves spontaneous breathing without endotracheal intubation, avoids the physical stimulation of intubation and the airway damage caused by mechanical ventilation. This approach may reduce the incidence of postoperative airway injury and respiratory failure, potentially expanding the indications for minimally invasive lung surgery, lowering postoperative complication and mortality rates. The aim is to further clarify the surgical indications for non-intubated single-port minimally invasive surgery in patients with impaired lung function, the decision-making criteria for postoperative ICU transfer, and the safety and feasibility of this comprehensive management approach.

This description comes directly from the study's public registry record.

Talk to the study team

Yunpeng Zhao  ·  18766188692  ·  zhaoyunpengsddx@sdu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

The Second Hospital of Shandong UniversityJinan, Shandong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06848751