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Study identifier: NCT06848660 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study on Orthosis in Cervical Spine Fracture Treatment

Condition: Cervical Spine Fractures · Cervical Spine Injury · Rigid Collar  ·  Sponsor: Uppsala University Hospital

PhaseNA
Planned participants616
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Background and Purpose: Neck fractures affect over 1,100 people in Sweden each year, with the majority being frail older adults. Most neck fractures are stable and therefore treated without surgery, typically using a rigid collar. However, the collar only limits neck movement by 40-50% and can cause pressure sores, as well as difficulties with swallowing and breathing. Because of these issues, the latest Swedish national guidelines for pre-hospital and hospital spinal motion restriction have replaced the rigid collar with other methods. This raises the question of whether the rigid collar still has a role in the modern treatment of stable neck fractures. The aim of this study is to determine whether treatment with or without a rigid collar leads to equally good healing outcomes. Method: All adults diagnosed with a stable neck fracture deemed suitable for non-surgical treatment will be included in the study at the time of registration in the Swedish Fracture Register (SFR). Participating hospitals will be randomly assigned (1:1) to either use no collar at all or a rigid collar for 12 weeks. After an initial period of 1.5 years, the hospitals will switch to the opposite treatment group. A total of 616 participants are expected to be included within 3 years. At the one-year follow-up, investigators will evaluate how many participants in each treatment group that required a switch to surgical stabilization due to treatment failure. Secondary outcomes will include quality of …

This description comes directly from the study's public registry record.

Talk to the study team

Anna MacDowall M Principal investigator, Associate Professor  ·  +46 186110000  ·  anna.macdowall@uu.se

Paul Gerdhem Head of Spine Department, Professor  ·  +46186110000  ·  paul.gerdhem@uu.se

Always discuss trial participation with your own doctor first.

Locations (6)

Sahlgrenska University HospitalGothenburg, SwedenRecruiting
Linköping University HospitalLinköping, SwedenRecruiting
Skåne University HospitalLund, SwedenRecruiting
Skåne University HospitalMalmö, SwedenRecruiting
Umeå University HospitalUmeå, SwedenRecruiting
Uppsala University HospitalUppsala, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT06848660