Condition: Soft Tissue Sarcoma (STS) · Sponsor: Sun Yat-sen University
This is a single-arm, open-label, non-blind, phase I/II clinical trial evaluating the safety and efficacy of umbilical cord blood natural killer (NK) cell in children with high-risk and relapsed/refractory soft tissue sarcoma (STS). Objective: Assess the safety and efficacy of NK cell in high-risk and relapsed/refractory STS patients. Observe the pharmacokinetics and pharmacodynamics of NK cells in these patients. Study Design: Single-arm, open-label, non-blind design. 40 patients with high-risk and relapsed/refractory STS will receive the NK cell combined with other treatment . The treatment regimen involves 8 doses of NK cells injected at specific time points over 3 months, followed by a 3-year follow-up period.
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| Sun Yat-sen University Cancer Center | Guangzhou, Guangdong, China | Recruiting |
| Dongguan Taixin Hospital | Dongguan, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06848582