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Study identifier: NCT06848309 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Dissecting Human Immune Responses to Infection With Influenza or SARS-CoV-2

Condition: Influenza · SARS-CoV-2 (COVID-19) Infection · Immune Response of Host  ·  Sponsor: Washington University School of Medicine

PhaseN/A
Planned participants300
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersYes

About this study

The purpose of this study is to evaluate the virus-specific immune response in people who are symptomatic with confirmed influenza or COVID-19. We will study the immune response of people who have and who have not been vaccinated with the seasonal influenza and COVID-19 vaccines within the past year. All participants will have data collected and blood, saliva, and nasal swabs performed at five separate visits; 1) at study enrollment, 2) on study day 7, 3) on or between study days 10 to 28, 4) on study day 90, and 5) on study day 180. For participants who agree to the optional sub-study, bronchoscopy with bronchoalveolar lavage (BAL) and endobronchial biopsy (EBBx) will be performed once between study days 10 and 28 and once at study day 180. As part of the bronchoscopy procedure, two chest x-rays will be performed. The bronchoscopy and chest x-ray procedures are not required for participation in the study.

This description comes directly from the study's public registry record.

Talk to the study team

Jamie Mills  ·  314-305-1054  ·  jamiem@wustl.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Washington University in Saint Louis Department of Emergency Medicine, Emergency Care Research CoreSt Louis, Missouri, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06848309