Condition: Carrier State · Heat Stroke · Dehydration · Sponsor: University of Iowa
The goal of this observational study is to examine the effect of the Cystic Fibrosis (CF) Carrier state on the risk for dehydration and other CF-specific fluid-and-electrolyte disorders in male and female adults. The primary aim of the study is to estimate the risk of electrolyte disorders attributable to the CF carrier state in a genotyped cohort. This will be accomplished with two smaller projects- Aim 1 and Aim 2. Aim 1 will consist of 100 CF Carriers and 100 age- and sex-matched controls. Participants in this aim will be asked to complete a Participant Info and Temperature Survey consisting of questions about race, ethnicity, medical history, and how they experience heat. Aim 2 will consist of a subset of 25 CF Carriers and 25 age- and sex-matched controls from Aim 1. Participants in this aim will be scheduled for a visit to complete a heat challenge. At this visit, they will also complete the Participant Info and Temperature Survey. They will also sit in a sauna at 62 - 63 degrees Celsius for 45 minutes.
This description comes directly from the study's public registry record.
Aaron Miller, PhD · (319) 335-3053 · aaron-miller@uiowa.edu
Shelby L Francis, PhD · 319-678-8037 · shelby-francis@uiowa.edu
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| University of Iowa Health Care | Iowa City, Iowa, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06847256