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Study identifier: NCT06846463 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Zanubrutinib in Patients With DLBCL and MYD88 or NOTCH1 Mutation or CD5+

Condition: Diffuse Large B-cell Lymphoma · DLBCL - Diffuse Large B Cell Lymphoma  ·  Sponsor: Virginia Commonwealth University

PhasePhase 2
Planned participants21
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is a single-arm, open label, non-randomized, phase 2 trial of zanubrutinib in patients with diffuse large B-cell lymphoma (DLBCL) who have an MYD88 L265P mutation, a CD79B mutation, a NOTCH1 truncation, or who are CD5+ by immunohistochemistry (IHC).

This description comes directly from the study's public registry record.

Talk to the study team

Massey IIT Research Operations  ·  804-628-6430  ·  masseyepd@vcu.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Virginia Commonwealth UniversityRichmond, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06846463