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Study identifier: NCT06846450 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase 3 Trial Comparing IMRT or IMPT Plus CIRT for Patients With NPC

Condition: Nasopharyngeal Cancinoma (NPC)  ·  Sponsor: Lin Kong, MD

PhasePhase 3
Planned participants470
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

The goal of this phase 3 non-inferiority trial is to compare the efficacy and toxicity of proton or photon radiation therapy plus carbon ion radiation therapy for newly diagnosed nasopharyngeal carcinoma. The main question it aims to answer is that if proton radiation therapy plus carbon ion radiation therapy is non-inferior to photon radiation therapy plus carbon ion radiation therapy in terms of therapeutic efficacy. Participants will be randomized to receive either proton radiation therapy (arm 1) or photon radiation therapy (arm 2), in addition to carbon ion radiation therapy (for both arms).

This description comes directly from the study's public registry record.

Talk to the study team

Lin Kong  ·  86-38296666  ·  konglinjiang@163.com

Jiyi Hu  ·  86-38296666  ·  jiyi.hu@sphic.org.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai Proton and Heavy Ion CenterShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06846450