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Study identifier: NCT06846281 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

Condition: Relapsing Multiple Sclerosis  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 3
Planned participants360
Who can joinAll sexes, 40 Years to 70 Years
Healthy volunteersNo

About this study

The purpose of this Phase 3b study is to assess the efficacy, safety and tolerability of remibrutinib after switching from ocrelizumab and compared to continuous ocrelizumab treatment, in patients living with relapsing multiple sclerosis (plwRMS).

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals  ·  1-888-669-6682  ·  novartis.email@novartis.com

Novartis Pharmaceuticals  ·  +41613241111

Always discuss trial participation with your own doctor first.

Locations (120)

Perseverance Research CenterScottsdale, Arizona, United StatesRecruiting
University of California IrvineIrvine, California, United StatesRecruiting
Medstar Washington Hospital CenterWashington D.C., District of Columbia, United StatesRecruiting
Neurology of Central FL Res CtrAltamonte Springs, Florida, United StatesRecruiting
University of FloridaGainesville, Florida, United StatesRecruiting
Neurology Associates PAMaitland, Florida, United StatesRecruiting
Aqualane Clinical ResearchNaples, Florida, United StatesRecruiting
Advent Health OrlandoOrlando, Florida, United StatesRecruiting
Orlando Health Clinical TrialsOrlando, Florida, United StatesRecruiting
Tallahassee Neurological ClinicTallahassee, Florida, United StatesRecruiting
University Of South FloridaTampa, Florida, United StatesRecruiting
Vero Beach NeurologyVero Beach, Florida, United StatesRecruiting

+ 108 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06846281