Condition: HIV · Obesity · Sponsor: VA Office of Research and Development
The Department of Veterans Affairs is the largest single provider of medical care to people with HIV in the United States. The condition of excess lipid within and around muscle, termed myosteatosis, predisposes Veterans to physical function decline, frailty, disability, and cardiometabolic diseases such as diabetes and cardiovascular disease. In the investigators current Merit supported cohort, the investigators found that 36% of Veterans with treated HIV and obesity have "myosteatotic type obesity". Based on the investigators findings, the investigators have designed a multipronged integrated intervention that combines: 1) dietary replacement of saturated with unsaturated fats; 2) administration of L-carnitine and omega-3 fatty acid supplementation; and 3) targeted resistance exercise training.
This description comes directly from the study's public registry record.
Heidi J Silver, PhD · (615) 875-9355 · heidi.j.silver@vumc.org
John R Koethe, MD · (615) 873-6188 · john.koethe@va.gov
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| Tennessee Valley Healthcare System Nashville Campus, Nashville, TN | Nashville, Tennessee, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06845046