← Eichor
Study identifier: NCT06844383 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate

Condition: Prostate Cancer (Adenocarcinoma) · mCRPC (Metastatic Castration-resistant Prostate Cancer)  ·  Sponsor: Prostate Cancer Clinical Trials Consortium

PhasePhase 2
Planned participants126
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to find out whether talazoparib in combination with enzalutamide or talazoparib alone delays cancer progression in people with metastatic castration-resistant prostate cancer (mCRPC) who have homologous recombination repair (HRR) mutations and have previously received abiraterone acetate.

This description comes directly from the study's public registry record.

Talk to the study team

Sarah Wise  ·  215-380-9051  ·  wises@mskcc.org

Always discuss trial participation with your own doctor first.

Locations (7)

City of HopeDuarte, California, United StatesRecruiting
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Masonic Cancer CenterMinneapolis, Minnesota, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Abramson Cancer Center of the University of Pennsylvania, Hospital of the University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting
Fred Hutchinson Cancer CenterSeattle, Washington, United StatesRecruiting
University of Wisconsin Carbone Cancer Center-MadisonMadison, Wisconsin, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT06844383