Condition: Ovarian Cancer · Lung Adenocarcinoma · Pancreatic Cancer · Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
The project aims to perform integrated PET/MR or PET/CT visualization of patients with clinically suspected or confirmed pancreatic cancer, ovarian cancer, lung adenocarcinoma and other malignant tumors with high MSLN expression and healthy volunteers, using targeted MSLN-specific imaging agents (taking \[68Ga\]Ga-NOTA-MSLN antibody fragment as an example), to achieve the following purposes: Patients with malignant tumors: for diagnosis and staging of diseases, comparing with the gold standard pathological diagnosis, evaluating diagnostic efficacy, clarifying the presence or absence of lesions, and determining the location and nature of lesions; comparing with \[18F\]FDG PET for accurate staging, evaluating the tumor load, and helping to determine the therapeutic plan. Healthy volunteers: Pharmacokinetic analysis will be performed to clarify the distribution and metabolism of the drug in the body and its safety.
This description comes directly from the study's public registry record.
Xiaoli Lan, PhD · 0086-027-83692633 · lxl730724@hotmail.com
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| Wuhan Union Hospital, China | Wuhan, Hubei, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06843629