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Study identifier: NCT06843525 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Bite Force Measurements

Condition: Irreversible Pulpitis · Apical Periodontitis · Pulpal Necrosis  ·  Sponsor: Rutgers, The State University of New Jersey

PhaseN/A
Planned participants112
Who can joinAll sexes, 18 Years to 89 Years
Healthy volunteersNo

About this study

ABSTRACT: Acute dental pain from untreated decay often drives patients to emergency rooms (ERs), where the lack of definitive dental treatment results in nearly 75% of these patients receiving analgesics, predominantly opioids. Addressing the need for non-opioid pain alternatives is crucial. Emerging evidence suggests that dental pain from pulpal and periodontal conditions (affecting the tooth's nerve and surrounding tissues) involves neuropathic mechanisms, such as mechanical allodynia (MA) and central sensitization (CS). These mechanisms can amplify pain perception, causing typically non-painful actions, like chewing, to become painful and resulting in hypersensitivity extending beyond the affected tooth. Reliably identifying these mechanisms with quantitative measures can support improved pain assessment and targeted non-opioid treatment. This minimally invasive prospective cohort study will use the FDA-approved Innobyte® device, a precise bite-force measurement tool, to evaluate periodontal health and to quantify mechanical pain thresholds in patients requiring endodontic treatment (root canal therapy).

This description comes directly from the study's public registry record.

Talk to the study team

Gayathri D Subramanian, PhD, DMD  ·  973 972 3418  ·  subramga@sdm.rutgers.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Rutgers School of Dental MedicineNewark, New Jersey, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06843525