Condition: Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) · Liver Fibrosis/NASH · Non-Alcoholic Steato-Hepatitis (NASH) · Sponsor: Université de Sherbrooke
Metabolic dysfunction-associated steatotic liver disease (MASLD) (aka non-alcoholic fatty liver disease), commonly occurring in individuals with obesity and type 2 diabetes can lead to liver inflammation/ fibrosis. MASLD results from fat being disproportionately deposited in the liver. The goal of this mechanistic study is to investigate metabolic response in patients aged 20 to 80 years with non-alcoholic fatty liver disease, after niacin (vitamin B3) treatment. The main questions it aims to answer are: * Does Niacin lower the fat deposition in the liver? * Does Niacin raise White Adipose Tissue storage of dietary fatty acids? Researchers will compare Niacin to a placebo (a look-alike substance that contains no drug) to compare the metabolic response. Duration of study per participant: Up to 28 weeks
This description comes directly from the study's public registry record.
Frédérique Frisch · 1-819-346-1110 · frederique.frisch@usherbrooke.ca
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| Centre de recherche du CHUS | Sherbrooke, Quebec, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06843148