← Eichor
Study identifier: NCT06842498 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Condition: Metastatic Castration-Resistant Prostate Cancer  ·  Sponsor: Kyntra Bio

PhasePhase 2
Planned participants75
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety, efficacy, tolerability, and pharmacokinetics (PK) of FG-3246, a cluster of differentiation 46 (CD46) targeting antibody-drug conjugate (ADC), in the treatment of participants with mCRPC who have progressed following treatment with one prior second-generation androgen receptor signaling inhibitor (ARSI) in any setting and no prior taxane therapy in the mCRPC setting.

This description comes directly from the study's public registry record.

Talk to the study team

Javier Moreno  ·  415-978-1466  ·  jmoreno@kyntrabio.com

Mairead Carney  ·  415-978-1337  ·  mcarney@kyntrabio.com

Always discuss trial participation with your own doctor first.

Locations (20)

Western Regional Medical Center - City of Hope Phoenix GoodyearGoodyear, Arizona, United StatesRecruiting
HonorHealth Research InstituteScottsdale, Arizona, United StatesRecruiting
The University of Arizona Cancer Center - North CampusTucson, Arizona, United StatesRecruiting
VA Greater Los Angeles Healthcare SystemLos Angeles, California, United StatesRecruiting
UCLA Clark Urology CenterLos Angeles, California, United StatesRecruiting
University of California San FranciscoSan Francisco, California, United StatesRecruiting
New Haven Hospital - Yale Cancer CenterNew Haven, Connecticut, United StatesRecruiting
Bioresearch Partner - AventuraAventura, Florida, United StatesRecruiting
Bioresearch Partner - HialeahHialeah, Florida, United StatesRecruiting
Winship Cancer Institute, Emory UniversityAtlanta, Georgia, United StatesRecruiting
East Jefferson General Hospital MetairieNew Orleans, Louisiana, United StatesRecruiting
New Mexico Oncology Hematology Consultants, Ltd.Albuquerque, New Mexico, United StatesRecruiting

+ 8 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT06842498