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Study identifier: NCT06842186 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase 1/2a Study of WVE-007 in Adults Living With Overweight or Obesity

Condition: Overweight and Obesity  ·  Sponsor: Wave Life Sciences USA, Inc.

PhasePhase 1/Phase 2
Planned participants296
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersYes

About this study

The purpose of this study is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of ascending doses of WVE-007 when administered subcutaneously (SC) . Part A is a single ascending dose study in adults living with overweight and obesity. The Part B of the study is a repeat dose administration in two adult populations: Pre Type 2 diabetes (Pre T2D) and Type 2 Diabetes (T2D) in adults who are affected by obesity.

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Operations  ·  855-215-4687  ·  Clinicaltrials@wavelifesci.com

Always discuss trial participation with your own doctor first.

Locations (6)

Parexel International-EPCU BaltimoreBaltimore, Maryland, United StatesRecruiting
ARENSIA Research ClinicChisinau, MoldovaRecruiting
Arensia Clinics S.R.L.Bucharest, RomaniaRecruiting
Spitalul Clinic Judetean De Urgenta ClujCluj-Napoca, RomaniaRecruiting
Parexel International Early Phase Clinical UnitHarrow, United KingdomRecruiting
Simbec-Orion Clinical PharmacologyMerthyr Tydfil, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06842186