Condition: Stroke · Upper Limb Function · Sponsor: University of Oxford
Non-invasive brain stimulation (NIBS) has the potential to boost rehabilitation after stroke by creating a 'pro-plastic' environment, where the brain is more adaptable in response to movement (motor) training. However, responses to classical NIBS protocols are highly variable. Movement-related changes in specific brain rhythms have previously been shown to be related to recovery of hand/arm function after a stroke. The investigators propose to use NIBS to target movement-related activity in the beta band (13-30Hz) within the motor cortical regions of the brain. The investigators will use a type of NIBS called transcranial alternating current stimulation (tACS), which uses a sinusoidally-varying electrical current where the stimulation frequency is determined to be relevant to the underlying brain rhythms of interest, and the stimulation timed to coincide with specific phases of the hand/arm movement. The primary aim is to investigate whether beta-tACS improves upper limb movement in stroke survivors.
This description comes directly from the study's public registry record.
Melanie Fleming, PhD · +44 1865 611461 · melanie.fleming@ndcn.ox.ac.uk
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| Oxford Centre for Functional MRI of the Brain (FMRIB) | Oxford, United Kingdom | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06842095