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Study identifier: NCT06841172 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Continuation of First-line Therapy With Radiotherapy Versus Early Switch to Second-line Therapy in Oligoprogressive HCC

Condition: OligoProgressive Metastatic Disease · Hepatocellular Carcinoma (HCC) · Radiotherapy  ·  Sponsor: Shandong Cancer Hospital and Institute

PhasePhase 3
Planned participants132
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This multicenter, prospective, randomized, controlled, open-label, two-arm Phase III clinical trial is designed to evaluate whether adding radiotherapy to oligoprogressive lesions while continuing first-line systemic therapy at the time of oligoprogression can effectively prolong progression-free survival compared to early switching to second-line systemic therapy in oligoprogressive hepatocellular carcinoma.

This description comes directly from the study's public registry record.

Talk to the study team

Jinbo Yue, Doctor  ·  0531-67626442  ·  jbyue@sdfmu.edu.cn

Jinbo Yue, Doctor  ·  jbyue@sdfmu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Jinan, Shandong 0531Jinan, Shandong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06841172