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Study identifier: NCT06839248 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Fasting Recommendations Among Patients Using GLP-1 Receptor Agonists

Condition: Residual Gastric Contents · Pulmonary Aspiration of Gastric Contents  ·  Sponsor: St Vincent's Hospital Melbourne

PhaseNA
Planned participants154
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The aim of this randomised controlled trial is to determine the effect of a 24-hour clear liquid diet compared to standard fasting guidelines on the proportion of participants who present with increased residual gastric contents during their study visit. It also aims to determine the effect of a 24-hour clear liquid diet compared to standard fasting guidelines on: * Solid content or thick fluids * Patient-reported outcome measures (PROMs), including thirst, hunger, nausea, fatigue, and anxiety. * Compliance measures, including adherence with the intervention, time since last oral intake of solid foods, and time since last oral intake of clear liquids. We will enrol adults who are currently using any once-weekly glucagon-like peptide-1 receptor agonist (GLP-1RA) medication. Participants will be allocated in a 1:1 ratio to follow a 24-hour clear liquid diet or standard fasting guidelines prior to attending a study visit where participants will undergo a blinded gastric ultrasound assessment.

This description comes directly from the study's public registry record.

Talk to the study team

Prof Michelle Dowsey, BHealthSci(Nursing), MEpi, PhD  ·  03 9231 3955  ·  mmdowsey@unimelb.edu.au

Jasmin Elkin  ·  jelkin@student.unimelb.edu.au

Always discuss trial participation with your own doctor first.

Locations (2)

Melbourne Gastro Oesophageal Surgery (MGOS)Melbourne, Victoria, AustraliaRecruiting
St Vincent's Hospital MelbourneMelbourne, Victoria, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT06839248