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Study identifier: NCT06839066 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase II Study to Evaluate HLX43 in Subjects With Recurrent/Metastatic Nasopharyngeal Carcinoma Failed or Intolerance to Second-line Therapy

Condition: Nasopharyngeal Carcinoma (NPC)  ·  Sponsor: Shanghai Henlius Biotech

PhasePhase 2
Planned participants70
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study is to explore the reasonable dosage and to evaluate the efficacy, safety and tolerability of HLX43 (Anti-PD-L1 ADC) in patients with recurrent/metastatic Nasopharyngeal Carcinoma (NPC) who failed or are intolerant to second-line herapy.

This description comes directly from the study's public registry record.

Talk to the study team

Wenhua Yu  ·  +86 17638575068  ·  Wenhua_Yu1@henlius.com

Always discuss trial participation with your own doctor first.

Locations (15)

Fujian Cancer HospitalFuzhou, Fujian, ChinaRecruiting
Dongguan People's HospitalDongguan, Guangdong, ChinaRecruiting
Sun Yat-sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting
The First Affiliated Hospital of Guangdong Pharmaceutical UniversityGuangzhou, Guangdong, ChinaRecruiting
Zhongshan City People's HospitalGuangzhou, Guangdong, ChinaRecruiting
Cancer Hospital Chinese Academy of Medical Sciences, ShenzhenShenzhen, Guangdong, ChinaRecruiting
Guangxi Medical University Cancer HospitalNanning, Guangxi, ChinaRecruiting
Guizhou Medical University Cancer HospitalGuiyang, Guizhou, ChinaRecruiting
Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science & TechnologyWuhan, Hubei, ChinaRecruiting
Union Hospital Tongji Medical College Huazhong University of Science and TechnologyWuhan, Hubei, ChinaRecruiting
Xiangya Hospital of Central South UniversityChangsha, Hunan, ChinaRecruiting
First Affiliated Hospital of Gannan Medical UniversityGanzhou, Jiangxi, ChinaRecruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06839066