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Study identifier: NCT06839001 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

CRYoablation for Small Tumors As Local Treatment - SIX Trial

Condition: Breast Cancer · Breast Neoplasm  ·  Sponsor: Hospital do Coracao

PhasePhase 3
Planned participants750
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

To demonstrate the non-inferiority of cryoablation compared to breast surgery for the local treatment of early-stage breast cancer and to conduct a cost-minimization analysis comparing direct costs between treatments.

This description comes directly from the study's public registry record.

Talk to the study team

Vanessa Monteiro Sanvido, PhD, Professor  ·  +55 11 5576484  ·  dravanessasanvido@gmail.com

Afonso Celso Pinto Nazário, PhD, Professor  ·  +55 11 5576484  ·  nazarioafonso@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

Research Institute - Hospital do CoracaoSão Paulo, São Paulo, BrazilNot Yet Recruiting
Research Institute - Hospital do CoracaoSão Paulo, São Paulo, BrazilRecruiting

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Source record: clinicaltrials.gov/study/NCT06839001