Condition: Ventilation Therapy · PEEP, Occult · CPR · Sponsor: Muehlenkreiskliniken, MKK
Out-of-hospital cardiac arrest (OHCA) remains a major cause of mortality, with low survival probabilities to hospital discharge. Despite the frequent use of airway management and mechanical ventilation during resuscitation, there is limited evidence regarding the optimal ventilation strategy to improve oxygen delivery and patient outcomes. The present study aims to investigate the effects of positive-end-expiratory-pressure (PEEP) set at 5 mbar compared to zero-end-expiratory-pressure (ZEEP) on the return of spontaneous-circulation (ROSC) in adult patients with OHCA.
This description comes directly from the study's public registry record.
Gerrit Jansen, PD Dr. med. · +49 571-790-54401 · gerrit.jansen@muehlenkreiskliniken.de
Jochen Hinkelbein, Prof. Dr. med. · +49 571-790-54401 · jochen.hinkelbein@muehlenkreiskliniken.de
Always discuss trial participation with your own doctor first.
| Emergency Medical Services | Gütersloh, North Rhine-Westphalia, Germany | Recruiting |
| JWK Minden | Minden, North Rhine-Westphalia, Germany | Recruiting |
| Emergency Medical Services | Osnabrück, Germany | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06836830