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Study identifier: NCT06836609 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH)

Condition: Metabolic Dysfunction-Associated Steatotic Liver Disease · Metabolic Dysfunction-Associated Steatohepatitis  ·  Sponsor: Regeneron Pharmaceuticals

PhasePhase 1/Phase 2
Planned participants132
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This study is researching an experimental drug called ALN-CIDEB, also referred to as "study drug". The study is focused on participants with metabolic dysfunction-associated steatotic liver disease (MASLD) (Part A) and metabolic dysfunction-associated steatohepatitis (MASH) (Part B). MASLD and MASH are long-lasting liver conditions caused by having too much fat in the liver. The aim of the study is to see how safe and tolerable the study drug is. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug * How the study drug works to change liver fat content * How much study drug and study drug metabolites (byproducts of the body breaking down the study drug) are in the blood at different times

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trials Administrator  ·  844-734-6643  ·  clinicaltrials@regeneron.com

Always discuss trial participation with your own doctor first.

Locations (4)

Arizona Liver HealthChandler, Arizona, United StatesRecruiting
Adobe Clinical ResearchTucson, Arizona, United StatesRecruiting
Richmond Pharmacology LimitedLondon, Greater London, United KingdomRecruiting
Parexel International Early Phase Clinical UnitHarrow, London, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06836609