Condition: ATTR Amyloidosis With Cardiomyopathy · ATTR-CM · ATTR Amyloidosis Wild Type · Sponsor: Medical University of Vienna
The objective of this prospective registry study is to comprehensively characterize the prevalence, (semi-) quantitative parameters, and associated clinical outcomes of mitral (MR) and tricuspid regurgitation (TR) in patients diagnosed with transthyretin amyloid cardiomyopathy (ATTR-CM). The study further aims to develop and implement new grading standards for the quantitative assessment of regurgitation severity, tailored to the distinct hemodynamic profile of ATTR-CM. This approach seeks to address the limitations of current regurgitation severity classifications, which do not adequately reflect the unique pathophysiology of a restrictive phenotype as seen in ATTR-CM.
This description comes directly from the study's public registry record.
Christian Nitsche, Priv.-Doz. Dr., PhD · +4314040048590 · christian.nitsche@meduniwien.ac.at
Laurenz Hauptmann, Dr. · +4314040048590 · Laurenz.hauptmann@meduniwien.ac.at
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| Medical University of Graz | Graz, Styria, Austria | Recruiting |
| Department of Internal Medicine II, Medical University of Vienna | Vienna, Austria | Recruiting |
| Medizinische Klinik und Poliklinik I, Klinikum der Universitaet Muenchen, Ludwig-Maximilians-University | Munich, Bavaria, Germany | Recruiting |
| Department of Cardiology, University Hospital Frankfurt, Goethe University | Frankfurt am Main, Hesse, Germany | Recruiting |
| Institute of Cardiology, ASST Spedali Civili di Brescia, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia | Brescia, Italy | Recruiting |
| Cardiologic Centre, Azienda Ospedaliero Universitaria di Ferrara | Ferrara, Italy | Recruiting |
| Center for Diagnosis and Treatment of Cardiomyopathies, Cardiovascular Department, Azienda Sanitaria Universitaria Giuliano-Isontina (ASUGI), University of Trieste | Trieste, Italy | Recruiting |
| University Medical Center Utrecht | Utrecht, Netherlands | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06836011