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Study identifier: NCT06835829 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Comparing Advanced Hemostasis and Ultrasound-Guided Puncture to Conventional Approaches in Distal Radial Access

Condition: Coronary Catheterization  ·  Sponsor: Associazione per lo Studio delle Malattie Cardiovascolari Cardiva ONLUS

PhaseNA
Planned participants480
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Meta-analysis results show that distal radial access (DRA) is associated with a significant reduction in the risk of radial artery occlusion compared to conventional transradial access (TRA). This is of paramount importance in an evolving interventional context where an increasing number of radial access procedures are being performed to address a growing number of independent health conditions. DRA is also associated with a lower rate of vascular access-related adverse events, establishing it as the safest vascular access ever. However, available data show that the success rate of DRA is lower than that of conventional TRA. Also, while the duration of hemostasis has been shown to be shorter, it has most likely not yet reached its full potential for shortening. Thus, the two extreme phases of DRA require important further evaluation. The CompAring uLtrasound-guided Puncture and advanced HemostAsis to cOnventional approaches in distal radial access: a dual randoMizEd praGmatic triAl (ALPHA\&OMEGA) trial will address this lack of knowledge by exploring whether a significantly shorter hemostasis duration can be achieved with DRA when using hemostasis enhancement and exploring whether ultrasound-guided puncture can increase the success rate of DRA.

This description comes directly from the study's public registry record.

Talk to the study team

Gregory A Sgueglia, MD, PhD  ·  +390651002864  ·  g.a.sgueglia@gmail.com

Always discuss trial participation with your own doctor first.

Locations (6)

Groupe Vivalia, Clinique Saint-JosephArlon, BelgiumRecruiting
CHU Charleroi-Chimay, Marie Curie HospitalCharleroi, BelgiumRecruiting
CHU Helora, Jolimont HospitalLa Louvière, BelgiumRecruiting
Sant'Eugenio HospitalRoma, RM, ItalyRecruiting
Sandro Pertini HospitalRoma, RM, ItalyRecruiting
Mater Salutis HospitalLegnago, VR, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06835829