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Study identifier: NCT06835595 Synced from ClinicalTrials.gov · July 29, 2026
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TMS-related Measures as Biomarker of Cognitive Impairment in PD

Condition: Parkinson Disease  ·  Sponsor: Azienda Sanitaria Universitaria Integrata del Trentino

PhaseNA
Planned participants52
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of the present study is to explore the diagnostic and prognostic value of neurophysiological biomarkers obtained through paired-pulse Transcranial Magnetic Stimulation (TMS) techniques in individuals affected by Parkinson's disease (PD) with and without cognitive decline. The main questions it aims to answer are: * TMS measures of cortical excitability are able to distinguish between PD patients cognitively normal, PD-Mild Cognitive Impairment (PD-MCI) and PD-Dementia (PD-D)? * TMS measures of cortical excitability are able to predict progression of PD patient cognitive status from cognitively normal to PD-MCI and PD-D?

This description comes directly from the study's public registry record.

Talk to the study team

Ruggero Bacchin, MD  ·  +39-0461903281  ·  ruggero.bacchin@apss.tn.it

Stefania Campostrini, MSc  ·  +39-0461903281  ·  stefania.campostrini@apss.tn.it

Always discuss trial participation with your own doctor first.

Locations (3)

SC Clinica Neurologica - Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI)Trieste, Friuli Venezia Giulia, ItalyNot Yet Recruiting
UOC Neuroriabilitazione - Azienda Sanitaria dell'Alto AdigeSterzing, Trentino-Alto Adige, ItalyNot Yet Recruiting
UOC Neurologia - Azienda Provinciale per i Servizi Sanitari (APSS)Trento, Trentino-Alto Adige, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06835595