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Study identifier: NCT06834867 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Multi-component Family Intervention to Lower Depression and Address Intimate Partner Violence in Nepal

Condition: Intimate Partner Violence (IPV) · Depression · PTSD - Post Traumatic Stress Disorder  ·  Sponsor: Possible

PhaseNA
Planned participants900
Who can joinAll sexes, 15 Years to 24 Years
Healthy volunteersNo

About this study

Intimate Partner Violence (IPV) is a major public health problem in low- and middle-income countries (LMICs). Globally, an estimated 30% of women report physical or sexual violence by an intimate partner in their lifetime. IPV is a well-established social driver of mental health problems, and doubles the rate of depression and post-traumatic stress disorder (PTSD). Interventions like cognitive behavioral therapy (CBT) can improve depression after women experiencing IPV exit abusive relationships. However, despite ongoing violence, many young women in LMICs are less likely to divorce or separate from their husband. But ongoing IPV severely limits mental health recovery and increases the risks of suicide. Another important factor in many LMICs is that young women often live in extended, multi-generational households, where studies have shown that mother-in-laws (MILs) play a critical role in young married women's autonomy and freedom of movement, substantially affecting her mental health. The pathways via which multiple family members and ongoing IPV affect young women's mental health in LMICs is very poorly understood. There is an urgent need to design and assess interventions that: a) improve mental health and reduce IPV; b) engage husbands and MILs, and not just women experiencing IPV; and c) elucidate pathways via which IPV-related drivers affect mental health. This study's research team, with over 16 years of experience in Nepal, conducted a pilot study introducing the Mu…

This description comes directly from the study's public registry record.

Talk to the study team

Bibhav Acharya, MD  ·  +1 917 653 9385  ·  Bibhav.Acharya@ucsf.edu

Sabitri Sapkota, PhD  ·  +977 9851031363  ·  sabitri.sapkota@possiblehealth.org

Always discuss trial participation with your own doctor first.

Locations (1)

PossibleKathmandu, Bagmati, NepalRecruiting

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Source record: clinicaltrials.gov/study/NCT06834867