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Study identifier: NCT06833749 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy and Safety of KBP-336 in Obese Individuals with Osteoarthritis

Condition: Osteoarthritis in the Knee · Obesity  ·  Sponsor: KeyBioscience AG

PhasePhase 2
Planned participants600
Who can joinAll sexes, 45 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if KBP-336 works to treat pain in osteoarthritis in individuals living with obesity. It will also learn about the effects on other parameters, such as quality of life and metabolism, as well as safety of KBP-336. The main questions it aims to answer are: * Does KBP-336 lower knee pain from osteoarthritis in individuals with obesity * Does KBP-336 lower bodyweight in the same population. Researchers will compare KBP-336 to a placebo (a look-alike substance that contains no drug) to see if KBP-336 works to pain and obesity Participants will: * Take KBP-336 or a placebo every week for 6 months * Visit the clinic once every 2 weeks for checkups and tests * Keep a diary of their symptoms and the amount of medication they use in addition to KBP-336

This description comes directly from the study's public registry record.

Talk to the study team

KeyBioscience AG Program Director, PhD  ·  +41 795207086  ·  rocco@keybioscience.com

Always discuss trial participation with your own doctor first.

Locations (20)

Pratia Brno, s.r.oBrno, CzechiaNot Yet Recruiting
L.K.N. ArtrocentrumHlučín, CzechiaNot Yet Recruiting
Medical Plus, s.r.oHradiště, CzechiaNot Yet Recruiting
Pratia Pardubice a.s.Pardubice, CzechiaNot Yet Recruiting
Affidea Praha s.r.oPrague, CzechiaNot Yet Recruiting
Pratia Prague, s.r.oPrague, CzechiaNot Yet Recruiting
Sanos Clinic NordjyllandGandrup, DenmarkRecruiting
Sanos Clinic HerlevHerlev, DenmarkRecruiting
Sanos Clinic SyddanmarkVejle, DenmarkRecruiting
Hong Kong Center for Clinical ResearchHong Kong, Hong KongNot Yet Recruiting
IMSP Sptalul Clinic Municipal "Sfanta Treime"Chisinau, MoldovaNot Yet Recruiting
PMSI Cardiology Institute/RTL SM SRLChisinau, MoldovaNot Yet Recruiting

+ 8 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06833749