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Study identifier: NCT06830876 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Detecting Change in Muscle Parameters, Pain, and Function With NMES for TTA

Condition: Amputation  ·  Sponsor: Sara Peterson-Snyder

PhaseNA
Planned participants20
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersYes

About this study

The proposal aims to investigate a non-invasive, cost-effective method for rebuilding muscle mass in individuals with transtibial limb loss. Maintaining a healthy, pain-free residual limb is a primary concern for prosthesis users. Amputees commonly experience muscle deficits leading to mobility issues, poor prosthetic fit, and chronic pain. Neuromuscular electrical stimulation (NMES) is a potential intervention that activates muscles with low-level electrical stimulation, improving strength, function, and reducing pain. The study seeks to understand NMES's effects on muscle parameters and pain to develop evidence-based interventions for amputees. Twenty participants with transtibial amputations will undergo an 8-week NMES training program. Ultrasound imaging will assess muscle thickness, cross-sectional area, and composition changes. The study aims to enhance mobility, prosthetic fit, and overall well-being of amputees, addressing challenges and reducing healthcare burdens.

This description comes directly from the study's public registry record.

Talk to the study team

Sara Peterson-Snyder, PhD  ·  4127363131  ·  sara@opclinicalinnovations.com

Kyle Leister, PhD  ·  Leister@mail.etsu.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Cranberry Township BuildingPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06830876