Condition: Toxicities · Survivorship · Sponsor: Shanghai Jiao Tong University School of Medicine
Conditioning regimen with melphalan-busulfan and fludarabine (MBF) achieved low relapse rate in patients with acute myeloid leukemia (AML) and myelodysplasia syndrome (MDS). In our previous retrospective study, we demonstrated that melphalan dose at 100 or 140mg/m2 had similar incidence of relapse but it might had lower toxicities. In this prospective randomize study, we aim to compare the transplantation outcome in adult patients with AML/MDS receiving either MBF with 100 or 140 mg/m2 melphalan.
This description comes directly from the study's public registry record.
Chun Wang · 86-13386259777 · Wangchunsh@mefmail.com.cn
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| Rui Jin Hospital | Shanghai, Shanghai Municipality, China | Recruiting |
| Zhaxin Hospital, Go Broad Health Care | Shanghai, Shanghai Municipality, China | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT06829472