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Study identifier: NCT06829355 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

"Thymalfasin Immunotherapy Study with Triple Regimen in Advanced MSS/pMMR Colorectal Cancer"

Condition: MCRC  ·  Sponsor: Beijing Friendship Hospital

PhasePhase 2
Planned participants52
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a multicenter, open-label, prospective, randomized controlled Phase II clinical study. All eligible subjects will be randomly assigned in a 1:1 ratio to either the triple therapy group or the double therapy group. Triple therapy group: Subjects will receive Thymalfasin in combination with Regorafenib and Tislelizumab until iCPD is achieved per iRECIST (progressive disease (PD) per iRECIST), or until an intolerable toxicity occurs; Double therapy group: Subjects will receive Regorafenib and Tislelizumab until iCPD is achieved per iRECIST (PD per iRECIST), or until an intolerable toxicity occurs.

This description comes directly from the study's public registry record.

Talk to the study team

Zhigang Bai, MD  ·  86-10-13511041528  ·  baizhigang@ccmu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Beijing Friendship Hospital, Capital Medical UniversityBeijing, China, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06829355