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Study identifier: NCT06829303 Synced from ClinicalTrials.gov · July 28, 2026
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BCI Training for Social Cognition and Error Monitoring in ASD

Condition: Autism Spectrum Disorder (ASD)  ·  Sponsor: University of Coimbra

PhaseNA
Planned participants28
Who can joinAll sexes, 16 Years to 55 Years
Healthy volunteersNo

About this study

Social cognition seems to develop atypically in autism, particularly in processes such as faces perception, joint attention and social information processing. In this sense, and using an Emotional Paradigm of Facial Expressions (EFP) with a Brain-Computer Interface (BCI) based on Electroencephalography (EEG), the investigators intend to evaluate its effectiveness as a medical device in Autism Spectrum Disorder (ASD), namely: improving 1) social skills and 2) reducing generalized anxiety, 3) improve error monitoring, and consequently verify 4) an increase in motivation. To this end, the investigators will test a gamified intervention (EFP), using personalized feedback in real time. In this gamified interface, there is an artificial agent that learns rules through Reinforcement Learning using the evoked potentials from the participant as they observe the agent's right or wrong actions. The hypothesis is that this approach allows, during the gamified task (EFP), not only the agent/interface to learn, but also the participant through operant conditioning and implicit scrutiny of errors, which makes it particularly interesting for disorders in which error monitoring processes are compromised, as in ASD.

This description comes directly from the study's public registry record.

Talk to the study team

Miguel Castelo-Branco  ·  +351239488510  ·  mcbranco@fmed.uc.pt

Always discuss trial participation with your own doctor first.

Locations (1)

ICNASCoimbra, PortugalRecruiting

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Source record: clinicaltrials.gov/study/NCT06829303