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Study identifier: NCT06828926 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment

Condition: Mild Cognitive Impairment (MCI) · Sarcopenia  ·  Sponsor: Ohio University

PhaseNA
Planned participants50
Who can joinAll sexes, 60 Years to no upper limit
Healthy volunteersYes

About this study

Mild Cognitive Impairment (MCI) in older adults is linked to muscle loss (sarcopenia) and can lead to dementia, with pain further impacting cognitive and physical performance. Tai Chi, a mind-body exercise, is recommended for managing MCI as it supports cognitive function, mood, and physical health. The investigators' first goal is to characterize the correlation of heart rate variability and cortical activity on cognitive function and the psychosocial correlates of pain interference and social isolation on cognitive function at baseline and post-intervention (8 weeks of Tai Chi). The second goal is to explain the role of sarcopenia and obesity in the relationship between pain interference and cognitive function. The investigators also want to examine the index of the predictive capacity regarding sarcopenia and obesity on cognitive function outcomes.

This description comes directly from the study's public registry record.

Talk to the study team

Nicholas Karayannis, MPT, PhD  ·  +1 740-593-1044  ·  nvkaray@ohio.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Ohio UniversityAthens, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06828926