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Study identifier: NCT06826456 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Er,Cr:YSGG Sub-Ablative Laser Irradiation on Fissure Caries Prevention in Permanent Molars

Condition: Caries,Dental  ·  Sponsor: Alexandria University

PhaseNA
Planned participants60
Who can joinAll sexes, 6 Years to 12 Years
Healthy volunteersYes

About this study

Background: Subjecting human dental enamel to sub-ablative laser has been suggested as a novel way of caries prevention. However, further studies are needed to establish its use as a routine clinical procedure for caries prevention. The aim of this study: This study aims to evaluate the effect of Er,Cr:YSGG subablative laser irradiation on caries resistance of occlusal fissures of permanent molars. Materials and methods: In-vivo study, a split mouth randomized controlled trial with sixty patients having two fully erupted bilateral first permanent molars (ICDAS-II score 0,1 or 2). The pits and fissures will be subjected to sub-ablative power of Er,Cr:YSGG Laser (Group 1, n=90) and will be compared with fluoride varnish application on the first permanent molars in the same arch(Group 2,n=90). DIAGNOdentTM readings and changes in ICDAS-II score will be assessed at base line and at 3,6,9 and 12 months follow-up.

This description comes directly from the study's public registry record.

Talk to the study team

Hussein Ezz Eldin  ·  +20 10 92403402  ·  hussein.ezz@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Alexandria UniversityAlexandria, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT06826456