Condition: Brain Function · Cerebral Palsy · Sponsor: IRCCS Fondazione Stella Maris
The goal of this study is to explore the anatomical-functional characteristics of the AON circuit (with particular interest for subcortical areas and the cerebellum), and the cortico-subcortical connectivity of the nodes of the AON circuit, using an ultra-high field (7T), high spatial resolution Magnetic Resonance Imaging protocol. The main questions it aims to answer are: * Can we demonstrate the involvement of subcortical areas and cerebellum in the AON circuit in each single-subject? * Can we obtain similar results in a small group of patients with Cerebral Palsy (CP), in order to demonstrate the feasibility of this approach for the study of the mechanisms of AON reorganization, after early brain damage? * Are different patterns of functional activation correlated to different clinical characteristics of CP patients? Participants will perform a 7 Tesla MRI scan, with a functional and anatomical dedicated protocol and will have a comprehensive clinical assessment before the MRI exam.
This description comes directly from the study's public registry record.
Laura Biagi, PhD · +39050886175 · laura.biagi@fsm.unipi.it
Giuseppina Sgandurra, MD · +39050886336 · giuseppina.sgandurra@fsm.unipi.it
Always discuss trial participation with your own doctor first.
| Fondazione IMAGO7 | Calambrone, PISA, Italy | Active Not Recruiting |
| IRCCS Fondazione Stella Maris | Calambrone, Pisa, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06826287