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Study identifier: NCT06824402 Synced from ClinicalTrials.gov · July 29, 2026
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Cryoprobe Biopsy and Chronic Rejection in Lung Transplant Recipients

Condition: Lung Transplant Rejection  ·  Sponsor: Mayo Clinic

PhaseNA
Planned participants100
Who can joinAll sexes, 18 Years to 99 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate which biopsy collection method helps to better diagnose rejection and relevant pathologic findings in lung transplant recipients. The main questions it aims to answer are: Does the 1.1 mm cryoprobe or the biopsy forceps provide better quality samples of lung tissue for detecting rejection in transplant recipients? How much tissue is adequate for lung transplant 1.1 mm cryobiopsy samples as compared to biopsy forceps? Which samples received by the pathologist did they find they were most confident to exclude rejection, based on their satisfaction with the samples? Which collection method has the least amount of procedural time? Researchers will compare lung tissue samples obtained using a 1.1mm cryoprobe and a biopsy forceps during the lung transplant. Participants will: Be randomly assigned to receive either the cryoprobe or biopsy forceps collection method at the time of biopsy. Assessed for any adverse events following the biopsy for up to 30 days after transplant.

This description comes directly from the study's public registry record.

Talk to the study team

John Joerns, MD  ·  507-284-6616  ·  joerns.john@mayo.edu

Jackie Reiter  ·  507-538-2224  ·  reiter.jacqulyn@mayo.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Mayo Clinic in RochesterRochester, Minnesota, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06824402