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Study identifier: NCT06824363 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

ProofPrincip IntraTu TCells SinglDoseImmunCheckpoinInhib Gastro-Esophage Adenocarcinoma w/ARID1a Mu

Condition: Solid Tumor, Adult · Malignant Solid Tumor · Stomach Adenocarcinoma  ·  Sponsor: University of California, Irvine

PhaseEARLY_Phase 1
Planned participants34
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a proof of principle clinical trial determining efficacy of single dose dualimmune checkpoint inhibitors to increase intra-tumoral T cells in esophageal, gastroesophageal junction, and gastric adenocarcinomas. These are subjects who have not previously been treated for their disease, who are willing to undergo biopsy procedures, who's disease has not spread to other parts of the body, who's tumors have ARID1A mutations.

This description comes directly from the study's public registry record.

Talk to the study team

Chao Family Comprehensive Cancer Center University of California, Irvine  ·  1-877-827-8839  ·  ucstudy@uci.edu

University of California Irvine Medical

Always discuss trial participation with your own doctor first.

Locations (1)

Chao Family Comprehensive Cancer Center, University of California, IrvineOrange, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06824363