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Study identifier: NCT06822010 Synced from ClinicalTrials.gov · July 29, 2026
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SeqUential GeMcitabine and MITomycin Treatment for Favorable High-Risk Upper Urinary Tract Urothelial Carcinoma

Condition: Urinary Bladder Cancer · Upper Tract Urothelial Cancer · Urothelial Cancer  ·  Sponsor: Rutgers, The State University of New Jersey

PhasePhase 2
Planned participants28
Who can joinAll sexes, 18 Years to 99 Years
Healthy volunteersNo

About this study

This Phase II clinical trial, titled "A Phase II Trial of Sequential Gemcitabine and Mitomycin Treatment for Favorable High-Risk Upper Urinary Tract Urothelial Carcinoma (SUMMIT)," aims to evaluate the safety and effectiveness of a combination chemotherapy treatment for patients with favorable papillary high-grade upper tract urothelial carcinoma (UTUC). The study focuses on sequential administration of two drugs, gemcitabine and Jelmyto (a gel-based form of mitomycin), to potentially preserve kidney function and avoid nephroureterectomy (kidney removal), which is the current standard of care for participants with non-endoscopically resectable tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Vignesh Packiam, MD  ·  732-235-2465  ·  VP624@cinj.rutgers.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Rutgers Cancer InstituteNew Brunswick, New Jersey, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06822010