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Study identifier: NCT06821100 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Thymalfasin (Thymosin Alpha 1; Ta1) as an Enhancer of Vaccine Response Among Older Adults Receiving Booster Doses of COVID-19 Vaccine

Condition: Vaccine Response · COVID-19 Vaccine · Immune Response to Covid 19 Vaccination  ·  Sponsor: The Methodist Hospital Research Institute

PhasePhase 1
Planned participants75
Who can joinAll sexes, 65 Years to 100 Years
Healthy volunteersYes

About this study

The goal of this research is to learn more about ZADAXIN® (trade name; thymalfasin generic; Ta1 for short) and determine if Ta1 has any benefit in increasing the immune response to the COVID-19 vaccine. Ta1 has been shown to stimulate the immune system to fight infections. This research study will test the safety and possible harms of Ta1 when it is given to people at different dose levels before COVID-19 vaccination.

This description comes directly from the study's public registry record.

Talk to the study team

Eleftherios Mylonakis, MD, PhD  ·  7134411576  ·  emylonakis@houstonmethodist.org

Always discuss trial participation with your own doctor first.

Locations (1)

Houston Methodist HospitalHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06821100