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Study identifier: NCT06820723 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety

Condition: Depression · Anxiety · Major Depressive Disorder  ·  Sponsor: Ohio State University

PhasePhase 2
Planned participants40
Who can joinAll sexes, 21 Years to 65 Years
Healthy volunteersNo

About this study

The goal of this study is to learn how psychedelics may help symptoms of depression and anxiety. Participants with major depressive disorder experiencing symptoms of depression and anxiety will receive one dose of either a drug related to psilocybin or a placebo. Assessments include interviews, self-report questionnaires, EEG and fMRI to measure symptoms and brain function.

This description comes directly from the study's public registry record.

Talk to the study team

Anne-Marie Duchemin  ·  6142935517  ·  anne-marie.duchemin@osumc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

The Ohio State University Department of PsychiatryColumbus, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06820723